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Exclusive interview: Sam Altman on Dev Day and AI's future

PLUS: Google releases Gemini Computer Use for AI browser control

Good morning, AI enthusiasts. Sam Altman just painted a picture of the future, and it's weirder than you think (but might not feel that way in the moment).

Between AI agents working autonomously for weeks, billion-dollar companies with zero humans, and a reimagining of what "work" even means, the OpenAI CEO just shared his latest predictions in an exclusive interview with The Rundown at Dev Day 2025.

Catch the full interview with Sam and Rowan on Twitter/X, YouTube, or Spotify.

In today’s AI rundown:

  • Sam Altman on Dev Day, AGI, and the future of work

  • Google releases Gemini 2.5 Computer Use

  • Create LinkedIn carousels in ChatGPT with Canva

  • Duke’s AI system for smarter drug delivery

  • 4 new AI tools, community workflows, and more

LATEST DEVELOPMENTS

OPENAI

Image source: The Rundown

The Rundown: We sat down with OpenAI CEO Sam Altman at Dev Day 2025 for a wide-ranging conversation on the company’s new launches, AGI, the future of work, the rise of AI agents, and more.

The details:

  • Altman said AI’s ability for “novel discovery” is starting to happen, with recent scientists across fields using the tool for breakthroughs.

  • Altman thinks the future of work “may look less like work” compared to now, with a fast transition potentially changing the “social contract” around it.

  • He believes Codex is “not far away” from autonomously performing a week of work, saying the progress of agentic time-based tasks has been disorienting.

  • The CEO also highlighted the potential for a zero-person, billion-dollar startup entirely spun up by a prompt being possible in the future with agentic advances.

Why it matters: Dev Day 2025 gave us a new step in both ChatGPT and OpenAI’s agentic tooling evolution, and Altman’s commentary provided an even deeper look into the future the company envisions. But no matter how strange the AI-driven changes get, Altman remains confident in humanity’s ability to adapt and thrive alongside them.

TOGETHER WITH SYNK

The Rundown: DevSecCon25 brings together AI and security experts for a free, one-day virtual event exploring how to empower AI innovation without compromising security — featuring Snyk's first-ever AI Security Developers Challenge.

Join DevSecCon25 for:

  • Keynotes from leaders at Qodo, Ragie AI, Casco, Arcade.dev, WorkOS, and more

  • Hands-on demos track covering how to build and secure with AI

  • An interactive developer challenge where you'll solve real AI security problems

GOOGLE

Image source: Google

The Rundown: Google released Gemini 2.5 Computer Use in preview, a new API-accessible model that can control web browsers and complete tasks through direct UI interactions like clicking buttons and filling out forms.

The details:

  • The model works by taking screenshots of websites and analyzing them to autonomously execute clicks, typing, and navigation commands.

  • Gemini 2.5 Computer Use outperformed rivals, including OpenAI Computer Using Agent and Claude Sonnet 4.5/4 across web and mobile benchmarks.

  • It also shows top quality at the lowest latency of the group, with Google revealing that versions of the model power Project Mariner and AI Mode tools.

Why it matters: While fully agentic computer use is still in its early days for mainstream users, the capabilities are rapidly maturing. Beyond the usual examples like booking appointments or shopping, countless time-consuming web tasks and workflows are waiting to be reliably automated.

AI TRAINING

The Rundown: In this tutorial, you will learn how to create professional LinkedIn carousels in minutes using ChatGPT's new Canva app integration, which gives you the ability to draft content and design slides all within a single interface.

Step-by-step:

  1. Go to ChatGPT, open a new chat, and click the '+' button to select Canvas, then prompt: "Write a 5-slide LinkedIn carousel on '(your topic)'. Slide 1: A hook. Slides 2-4: One tip each. Slide 5: A CTA. Keep each under 40 words"

  2. Refine your content in Canvas, then activate Canva by prompting: "@canva, create a 5-slide LinkedIn carousel using this content [paste slides]. Use a (detailed style of your choice). Stick to the content copy exactly" (First time: connect Canva in Account Settings → Apps and Connections)

  3. Preview the 4 design options ChatGPT generates, select your favorite, and click the Canva link to open your editable carousel

  4. Review each slide in Canva, make any final tweaks, then click Download and select PDF for LinkedIn documents or PNG for individual slides

Pro tip: Use your brand colors and fonts consistently — once you prompt them in chat, the integration applies them automatically to the carousels.

PRESENTED BY IBM

The Rundown: IBM Network Intelligence introduces a new human-AI model that blends analytical AI with “reasoning” AI — a dual approach developed to help enterprises filter noise, identify issues, and scale operations seamlessly.

With IBM Network Intelligence, you’ll experience:

  • Fast, accurate insights

  • AI that scales while humans guide strategy

  • Less tool bloat, more efficiency

AI & MEDICINE

Image source: Reve / The Rundown

The Rundown: Duke University researchers introduced TuNa-AI, a platform that combines robotics with machine learning to design nanoparticles for drug delivery, showing major improvements in cancer treatment effectiveness.

The details:

  • TuNa tested 1,275 formulations using automated lab robots, achieving a 43% boost in successful nanoparticle creation compared to traditional methods.

  • The team successfully wrapped a hard-to-deliver leukemia drug in protective particles that dissolved better and killed more cancer cells in tests.

  • In another win, they cut a potentially toxic ingredient by 75% from a cancer treatment while keeping it just as effective in mice.

  • TuNa handles both material selection and mixing ratios simultaneously, overcoming limitations of existing methods that can handle only one variable.

Why it matters: Many drugs fail not because they don’t work, but because they can’t reach their targets effectively. AI-powered solutions like TuNa could potentially turn previously shelved drugs into viable options, as well as help identify and design new safe and effective therapy options for some of the world’s trickiest diseases.

QUICK HITS

  • 📱 Apps SDK - Chat with and build apps directly in ChatGPT

  • 👁️ Hunyuan-Vision-1.5-Thinking - Tecent’s advanced vision-language model

  • 🔎 PromptSignal - See how LLMs rank your brand

  • 🧫 Petri - Anthropic’s open-source agentic tool for evaluating LLM safety

xAI launched v0.9 of its Grok Imagine video model, featuring upgraded quality and motion, native synced audio creation, and new camera effects.

Tencent released Hunyuan-Vision-1.5-Thinking, a new multimodal vision-language model that comes in at No.3 on LM Arena’s Vision Arena leaderboard.

Consulting giant Deloitte announced a new ‘alliance’ with Anthropic that will deploy Claude across its 470,000 employees.

YouTuber Mr. Beast commented on the rise of AI video capabilities, calling it “scary times” for millions of creators making content for a living.

IBM is also partnering with Anthropic to integrate Claude into its AI-first IDE and enterprise software, reporting 45% productivity gains across 6,000 early adopters.

COMMUNITY

Every newsletter, we showcase how a reader is using AI to work smarter, save time, or make life easier.

Today’s workflow comes from reader Nicole B. in Moscow, ID:

"I own a coffee roasting company and used Replit to create a roasting schedule. I gave Replit the coffees and blend recipes, and the amount of weight green beans lose in the roasting process and we can give it our coffee orders and get back a total amount of green coffee that needs to be roasted for each coffee origin."

How do you use AI? Tell us here.

That's it for today!

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Rowan, Joey, Zach, Shubham, and Jennifer — the humans behind The Rundown

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